Introduction

Tumor immunology is the study of interactions between the immune system and tumors. It is also a growing field ofresearch that aims to understand the mechanisms involved in immune evasion andto discover innovative cancer immunotherapies to treatand retard progression of this disease. The immune response, including therecognition of tumorantigensis of particular interest in this field as knowledge gained drives thedevelopment of new vaccinesand antibody therapies. Tumorsare not just a mass of proliferating genetically abnormal cells, but they arenow well defined as a heterogeneous and structurally complex microenvironment.Therefore, understanding and breaking the tumor suppressive microenvironmentare also the hot points of tumor immunology.

Our focus

We currently focus on the following aspects of tumorimmunotherapy: 1) In order to promote the anti-tumor immune response，we search for effective reagents，including small molecular drugs and cytokines，to prevent tumorcells from secreting immuno-suppressive cytokines such as TGF-β and IL-10.2) Screen for tumor-specific antigens andmolecular markers to provide targets for immuno-diagnosis and treatment ofcancer. 3) Explore the immune evasion mechanisms of tumor cells in aspects ofthe tumor cells themselves, the surrounding microenvironment and the hostdefense system. 4) Genetically modify certain viruses with relativelylow-virulence into special tumor-destructive viruses. Take advantage of thedefective tumor-suppressive genes to specifically infect, replicate in, anddestroy tumor cells. 5) Inoculate host with tumor vaccines to stimulate theimmune system and activate anti-tumor immune responses.